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便携式拉曼光谱仪在制药行业中的应用

便携式拉曼光谱仪在制药行业中的应用

本文关键词: 生物医药Raman
摘要

前言

YAOPINDEZHILIANGYUQILIAOXIAOMIQIEXIANGGUAN,ERYUANFULIAODEJIANYANSHIZHILIANGKONGZHILIUCHENGZHONGDEGUANJIANBUZHOU,BIANJIE、WENDINGHEKEKAODEWUZHIJIANCEBIAOZHENGSHOUDUANJIANGBIBUKESHAO。LAMANGUANGPUFASHIWUZHIBIAOZHENGDECHANGYONGFANGFAZHIYI,GAIFANGFAJIYUGUANGYUWUZHIXIANGHUZUOYONGDELAMANSANSHEXIAOYING,DUIBUTONGWUZHIJUYOUZHIWENTEZHENG;DABUFENWUJIDUOYUANZIYANLEI、DUOSHUYANGHUAWU、YOUJIRONGJI、TANGLEI、DIANFENHEJUHEWUDENGHUAHEWUDOUJUYOUTEZHENGDELAMANGUANGPU,BINGQIELAMANGUANGPUCESHIHAIJUYOUWUSUN、KUAISU、YANGPINYONGLIANGXIAOHEWUXUFUZAZHIYAODENGYOUSHI。

HAIYANGGUANGXUEDEAccuman PR500 BIANXIESHILAMANGUANGPUYISHIYONGYUYAOCHANGDEYUANFULIAOJIAN,GAIYIQIYOUSHOUCHIDUANYUZHUJIXIANGLIANGBUFENZUCHENG,QIZHONGSHOUCHIDUANYONGYUCEYANG,ZHUJIXIANGZEJICHENGLEGUANGPUYIHEJIFAGUANGYUAN,ERZHETONGGUOGUANGXIANLIANJIE,GUANGXIANWAICEBAOGUOYOUJUHEWUBAOCAI,KESHIXIANLINGHUODIWANQU。GAIGUANGPUYICAIYONGLE785nmDEBANDAOTIJIGUANGQIZUOWEIJIFAGUANGYUAN,KEYOUXIAOBIMIANWUZHIZAIKEJIANGUANGFANWEINEIYINGGUANGXIANXIANGDUILAMANXINHAODEYINGXIANG。

ACCUMAN PR-500      ACCUMAN PR-500

Accuman PR 500便携式拉曼光谱仪及测样现场

GAIGUANGPUYIJUYOUYOUHUADECAOZUOLIUCHENG,SHIDECAOZUORENYUANZHIXUHENSHAOBUZHOUJIKEWANCHENGJIANCE。ZAISHOUCHIDUANJIKESHIXIANJIANDANSAOMIAO、JIANLIBIAOZHUNWUZHISHUJUKU、JIANLIJIANBIEFANGFADENGSUOYOUCAOZUOJIJIEGUOXIANSHIGONGNENG。TONGSHI,GAIGUANGPUYIHAISHEZHILEJUYOUBUTONGCAOZUOQUANXIANDEGUANLIYUAN、CAOZUOYUANHEGONGCHENGSHISANLEIZHANGHAO,BAOZHENGSHUJUWANQUANXINGHEBUKECUANGAIXING。

管理员 工程师 操作员

万人炸金花Accuman PR 500BUTONGQUANXIANDECAOZUOJIEMIAN(GUANLIYUAN;GONGCHENGSHI;CAOZUOYUAN)

 

万人炸金花GUANLIYUAN:FUZEGUANLIZHANGHAO,DANWUCEYANGQUANXIAN;

GONGCHENGSHI:YOUCEYANGQUANXIAN,KEJIANLIFANGFA、BINGJINXINGJIANDINGJIFENXI;

CAOZUOYUAN:YOUCEYANGQUANXIAN,DANBUKEJIANLIFANGFA,KEXUANZEYIYOUFANGFAJINXINGJIANDING

万人炸金花Accuman PR 500GUANGPUYIDEXINGNENGQUANMIANFUHEZHIYAOXINGYEXUYAOZUNSHOUDE21CFR Part11 & Part 1040BIAOZHUN。BINGQIE,WOMENTIGONGWANSHANDE3QJIANYANWENDANG、YIQIXIAOZHENGHEDINGQIWEIHUFUWU。

 

应用举例

HAIYANGGUANGXUEAccuman PR 500BIANXIESHILAMANGUANGPUYIKEYIYONGYUZHIYAOYUANFULIAOHUOZHEBAOZHUANGCAILIAOYIJICHENGPINYAOWUDEDINGXINGHEDINGLIANGFENXI,RUYUANFULIAO、BAOZHUANGCAILIAO、YAOWUJIANBIE,YAOWUJINGXINGJIEGOUJIANBIEDENGFANGMIAN。

1. 原辅料鉴别—搜索与匹配功能

万人炸金花CHANGGUIYAOWUZHONGJIAOCHANGYONGDEJIZHONGYUANFULIAO,BAOKUOLINSUANQINGERNA、LINSUANERQINGNA、CUSUANNA、YINGZHISUANMEI、JUWEITONG、XIONGXIANWUTAI、LAOANSUAN、BANGUANGANSUAN、BINGANSUAN。SHIYONGAccuman PR 500,TONGGUOJIANLIBIAOZHUNYANGPINSHUJUKU,KEYIFANGBIANDIDUIXINJINDEYUANFULIAOJINXINGJIANDING。XIAMIANWEICUSUANNA、GANLUCHUN、LINSUANERQINGNAHEYINGZHISUANMEIDELAMANPUTUDEJIANSUOJIYUBIAOZHUNSHUJUKUDEPIPEIJIEGUO。

醋酸钠拉曼标准图谱和搜索匹配结果

TU1、CUSUANNALAMANBIAOZHUNTUPUHESOUSUOPIPEIJIEGUO

甘露醇拉曼标准图谱和搜索匹配结果

万人炸金花TU2、GANLUCHUNLAMANBIAOZHUNTUPUHESOUSUOPIPEIJIEGUO

磷酸二氢钠拉曼标准图谱和搜索匹配结果

万人炸金花TU3、LINSUANERQINGNALAMANBIAOZHUNTUPUHESOUSUOPIPEIJIEGUO

硬脂酸镁拉曼标准图谱和搜索匹配结果

TU4、YINGZHISUANMEILAMANBIAOZHUNTUPUHESOUSUOPIPEIJIEGUO

 

万人炸金花WOMENKEYIKANDAO,TONGGUOYUSHUJUKUZHONGDEBIAOZHUNPUTUDEPIPEI,CUSUANNA、GANLUCHUN、LINSUANERQINGNAHEYINGZHISUANMEIDENGFULIAOBEIZHUNQUEDISHIBIE。

 

2. 原料及成品药测定—测量分析功能

万人炸金花WOMENDUITOUBAOFUXINHETOUBAOLADINGDENGYUANLIAO,HUISANLIUYAOPIANJINXINGLECELIANG,TAMENJUNJUYOUTEZHENGDELAMANPUTU。

头孢呋辛

TU5 TOUBAOFUXINYUANLIAODELAMANPUTU

 

头孢拉定

万人炸金花TU6 TOUBAOLADINGYUANLIAODELAMANPUTU

图7 茴三硫药片的拉曼谱图

万人炸金花TU7 HUISANLIUYAOPIANDELAMANPUTU

结论

万人炸金花Accuman PR500BIANXIESHILAMANGUANGPUYIKEYINGYONGYUZHIYAOXINGYEZHONGDEYUANFULIAOHECHENGPINYAOWUDEJIANBIEHEFENXI,JUYOUKUAIJIE、KEKAO、KECHUANTOUTOUMINGJIBANTOUMINGBAOZHUANGZHIJIECEDINGERWUXUQUYANGDENGXIANZHUDEYOUDIAN。

  View: JIEJUEFANGAN-FENLEI: GAOGUANGPU

光纤光谱仪